What's your normal pain level daily? I actually have psoriatic arthritis as opposed to AS (but because I'm HLA-B27+ and have spinal involvement I consider it a close relative to AS, and I suppose because I tested for high levels of klebsiella as well). I think about mine more on an affected joints and their current pain vs whole body, as they seem to vary a decent amount day to day.

What meds do you take currently? Supplements? I'm currently only taking an Rx NSAID (meloxicam) and LDN. I was on sulfasalazine for a month about a year ago, but stopped that against my rheumy's wish for fear that it's antimicrobial effects would further damage my gut. I think she's ok with it now that my CRP dropped into normal range with the no starch diet.

I played rugby and did crossfit before my body started to break down. Now I try to keep up that intensity on the indoor rower. That's one of the reasons I'm fighting to figure this out, I miss that tremendously.

I'm not concerned about companies trying to make a profit, I just wish cures were more profitable to research, and that I had enough money to be in that room listening in and investing haha.