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You have to realize that there are parts of the immune system that also control inflammation. For example Interleukin 10 and IL 27 are cytokines that reduce inflammation and cancel out the effets of the pro-inflammatory cytokines like IL 23 and IL 17. The trick is to stimulate the right part of the immune system that can help and not the part that will make it worse.
Penn State has LDN in a phase 2 placebo controlled trial for crohns and the result look to be very promising. Crohns is an inflammatory disorder related to AS. I have not found a specific trial with LDN for AS either unfortunately.
The NIH has given Penn STate $500,000 to continue the research into LDN. They don't give that out if the research is not promising. Those grants are very competitive.
Last edited by drizzit; 04/15/0909:28 PM.
No families take so little medicine as those of doctors, except those of apothecaries.
