My mom has MS and I am on a TNF <simponi>. They are not ruled out in our case but the Doc needs to know and watch you closely.
I am approaching two years now and no MS signs. In the studies most developed the symptoms in the first year or less on the TNF and most saw the MS like symptoms go away when they stopped the TNF. (not all though)
It is very rare side effect but a scary one.
Valsmum -- Orencia is not a TNF so I am not sure MS type situation are related to it like the TNF drugs can be.