Oh, I don't think I knew that about your family history. Really glad to know that it doesn't rule out the possibility of a biologic, especially for those who really need to improve their quality of life.
It may make the decision tougher, but if you have a good Rheumatologist to keep a close eye, then these facts can all help to provide a level of comfort. I've read the same as you -- that studies have found it is very rare, that the symptoms most often reverse upon stopping the medication, and that the initial few months are the more important to watch, with the risk further decreasing from there.
A balanced and thoughtful post as ever, drizzit - thanks!
