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Joined: Feb 2002
Posts: 942
Senior_AS_Kicker
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Senior_AS_Kicker
Joined: Feb 2002
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Ken, In reply to:
It should not be confused with traditional sepsis
Yes, now that I have done more research I see in the allopathic literature references made to "bacterial translocation."
- Bacterial Translocation
- The passage of viable bacteria from the gastrointestinal tract to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the intestinal mucosa resulting in increased intestinal permeability. These mechanisms can act in concert to promote synergistically the systemic spread of indigenous translocating bacteria to cause lethal sepsis. Source: National Library of Medicine
There is clear evidence in subjects with immune deficiency, surgical stress and trauma that intestinal bacteria can pass across the intestinal wall thus reaching extra-intestinal sites but this can occur also under normal conditions. This process is controlled by the endogenous digestive microflora and the maintenance of a normal intestinal microecology is particularly crucial to limit the translocation of pathogen organisms. The mechanisms of translocation are still unclear but it probably occurs also in the presence of an intact intestinal mucosa as a result of bacteria being taken up by enterocytes or macrophages. As a matter of fact, the probability of translocation is greatly increased when the concentration of a particular bacterial species increases within the intestinal lumen and also when the mucus layer is reduced or eliminated probably because these combined mechanisms allow bacteria to adhere to, and be taken up by, the enterocyte surface. As a consequence, the probability of bacterial translocation to extraintestinal sites is greatly increased under these conditions.
Source: Edwards, C. How can we protect the gut microbial ecosystem? http://h0.web.u-psud.fr/microfun/ch8.html Best regards, jcwinnie 
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