Hi, alibat:


Professor Ebringer wanted to be very clear in his scientific observations, so he did studies on B27+ individuals only.

It was his general feeling, however, that B27-ves would also benefit from the diet; he just never included them in his scientific testing. He did, however, suggest every AS patient, regardless of antigen status, try his LSD (London AS Diet).

Quote:
Everything I've read about it suggests that it is the interaction of kiebsiella with the HLA- B27 molecule that is believed to be the basis of the success in some individuals of the diet, so being negative I wouldn't expect it to work if this is indeed the basis of it's success.


In truth the molecular mimicry explanation has been well studied and the mechanism defined in B27 individuals because the structure of the Osp (Outer surface protein) is well known. However, there are other antigens associated with AS and these also have similar sequences; the mistaken identity works the same way in each, and it is most likely there is only one mechanism for all AS. The same underlying disease for Crohn's, Reiter's, and perhaps even Behcet's (as many of these patients also respond to dietary starch restriction).

HEALTH,
John




Important AS Resources

Professor Ebringer: On Diet and AS;


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