Thanks for that Drizzit,
I didn't know much about the first function of ERAP1 that you mentioned, the ability to cleave cytokine receptors bound to cell surfaces, destroying their functionality as messengers and therby influencing inflammatory processes.
You mentioned that cells are triggerd to self destruct.
The term apoptosis is used to indicate programmed cell death, that is cell death that occurs in a way such that if the cell were virally infected viable viruses would not be released, that is, apoptosis as opposed to simple cell lysis.
Cheers David
