Misfolding protein seems to have become life science's eqivalent to string theory in physics - the answer to everything. Lots of theorising, nothing in the way of experimental evidence. Name the diseases which have been experimentally demonstrated to be the result of misfolding. It is getting to be a big yawn.


'Then you should say what you mean,' the March Hare went on. 'I do,' Alice hastily replied; 'at least - at least I mean what I say - that's the same thing , you know.' 'Not the same thing a bit!' said the Hatter.