Hello Sue,

I am new to this support group, however, I've been battling AS since i was 15 years old. I am now 25 and seem to have a decent handle on this out of control disease. I am on humira and have been on enbrel, and remicade before as well. My best friend is now Humira. it has had the best effects not only on my pain, but also on the symptoms with my eyes. i have had very little side effects, really none that i can think of. The list of side effects is very long and scary, but from first had experience, I've not had any of those. Of course you need to remember that medicine reacts differently for everyone, i have heard that some people do not benefit from it at all. The two week shots are better than the 1 x wk for enbrel, and the shot itself does not hurt as bad during injection. just make sure you let it get warm for about 15 min. before injection, that makes it easier too! Also, the pens suck!!! The pre-filled sirynges are much better for me. Good luck with it all. Oh, and one more thing before I go, pairing Humira with another drug sometimes helps more too. I am paired with Arava. most others I have spoken with are paired with Methotrexate (MTX) but that was like being on chemo for me, hair fell out, I was sick everyday and could not eat. just some info about that too! Good luck, let me know how you do.