No MTX for me. The first time I was on it, I don't remember having any serious side effects from it, but then it starting affecting my liver. I went off it, then my rheumy had me restart it. Not only did my liver still not like, I didn't like it either - I starting having more side effects with it. So stopped it again because of the liver.
When I changed rheumies, she had me try it one more time. This time it made me deathly sick every week when I took, plus my liver enzymes shot up immediately. Just not a good drug for me.
I take Plaquenil, Sulfasalazine & recently (reluctantly) went back on NSAIDs (Relafen).
Is the bone necrosis more of a side effect with Humira rather than Enbrel? I really need to read through the side effects list a little better for these drugs.
Sometimes I think I'm better off not looking at it too close though!
You're so right though about being between a rock & a hard place - I often say I take these drugs to fix one problem, only to have 2 more take its place it seems.
Do you take MTX or any other DMARDs? Maybe your doc could try adding/increasing one of them with your Enbrel to see if that will boost the effectiveness of it for you if you haven't tried that already without the added worry of Humira side effects.
Keep us posted how it goes.
