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#500568 02/13/14 02:24 AM
Joined: Dec 2013
Posts: 169
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First_Degree_AS_Kicker
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Hoping I can get a few opinions for my somewhat personal(not anymore) situation. Maybe others can relate?

Mollyc posted these two articles in the highlights and research section on KA.org: they're both really short, I promise smile

http://www.rheumatologynetwork.com/rheum...paradigm-change
(#6 and #7 of this article and at the end where it briefly mentions enhancing immunity as opposed to suppressing it interested me)

http://www.rheumatologynetwork.com/arthr...ay-promise-cure


The FIRST and WORST ank spond flare up I ever had was about 6-7 years ago. What I've come to realize only lately is that at the EXACT same time and JUST prior to my flare ups, I had Chlamydia trachomatis (C. trachomatis) It was confirmed in the hospital and I'm sure that it was treated improperly with the incorrect kind and dose of antibiotics because it came back shortly thereafter and was given a totally different kind of AB's for a different duration from a different hospital.

I'm hla-b27 but I KNOW that my AS derived from this.

This is a quote from the first article, section 7, "the authors point out that these pathogens may persist in the synovium, triggering a chronic inflammatory process that may last for years."

I have two questions;

1. Is it possible that over time and with poor health practice, these pathogens can colonize different areas wherever synovial fluid and/or hyaluronic acid is present? From back, to neck, to eye, to... in my case. Synovial fluid seems to be everywhere that people note auto-immune/arthritic/AS symptoms, including the eyes and skin for uveitis and psoriasis etc.

2. Based on the articles above and with my past and present situation, what kind of Antibiotic protocol would you take if you were in my shoes, if any? Would/should it be altered from what Dragon Slayer has had success with(tetracycline, cipro and flagyl), the Marshall protocol(sulfa-trimeth, minocycline, clindamycin and azithromycin), the basic Road back protocol(tetracycline usually in the form of minocin, along with???), what the second article used(rifampicin,doxycycline,azithromycin) to specifically target personal bacterial infections? I can worry about dosages and durations at a later time.

I have spoken with Dr. Blaney from this video;
http://www.youtube.com/watch?v=X0y0PcVJ5Ss
but he hasn't specifically mentioned which AB's would be used other than the fact that they would be bacteriostatic. I'm assuming similar approach as marshall protocol, AP-wise.

The nearest roadback Dr. for me is a plane ride away.
I need to see my rheumy in a week.

I'm open to all thoughts, opinions, negative or positive and right, wrong or unsure.

Joined: May 2010
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You could look at the work of Carter at South Florida :

http://www.ncbi.nlm.nih.gov/pubmed/20155838

And this group in Denmark

http://www.ncbi.nlm.nih.gov/pubmed/23404353

Both of these studies got a lot of discussion among arthritis researchers. There might be ideas in these studies about antibiotics.

Another tack to take with your doctor is to just use minocyline long term as it was considered a arthritis drug before the newer ones came out. It is antibiotic and anti-inflammatory.

Also, you could ask about an arthritis doctor who treats persistent infections over at Lymenet.org. Lots of so-called Lyme doctors will treat arthritis with antibiotics.

Good Luck.
Mary
Oh, editing here: I see that your second article basically summarizes Carter's work. Give that you think you had Chlamydia T., I would try his protocol.

Last edited by marypart; 02/13/14 04:02 AM.
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That makes perfect sense. I always thought it played a bigger role in the pathogenesis but this links it eloquently to the life of the disease and thus doesn't play a role. Its peptide does.

I really need to catch up on my reading

Last edited by Tnate; 02/13/14 05:32 AM.
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Thanks Mary. That article from pubmed will be a lot more reputable as far a my rheumy is concerned. More ammunition for my conversation. That's a great idea about potentially finding a lyme doctor nearer to my city. How can a city with over 3.5 million people NOT have a road back trained Doctor?

Tnate, as I read your post, I have another browser window already open for a speedreading program that I was considering buying. Too much to read. Mostly too technical for myself but at least I'd be able to not understand even FASTER wink

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I don't know much about antibiotics because I am allergic to them, but I have read that cipro has a LOT of bad side effects.

And have you checked for a Marshall Protocol doctor in your area? A doctor that is familiar with the Marshall Protocol would most likely be willing to do just the antibiotic part of the protocol, they're usually not married to the whole thing.

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I've found a naturopathic Doctor that is open to AB protocols. Their website lead me to other resources with a few variations to the protocols.

This site lists their own and has links to two other protocols as well:
http://arthritistrust.org/how-to-get-well/

I've noticed that the office I will be visiting facilitates 'ozone therapy by major autohemotherapy aka ultraviolet blood irradiation.' Not that you are on the hunt for anti-viral/anti-bacterials or anything Violeta but this would be a way to attack them without any allergic reactions to anti biotics...in theory.
http://www.pannaturopathic.com/oxidative.html


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