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Joined: Jun 2013
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How effective is it for you?
What dose do you use to fight pain?
Which side effects did you experienced?

Joined: Mar 2013
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When I was still in lots of pain, I found paracetamol almost ineffective - like throwing paper planes at the front of a bus.

For me, the side effects were brain fog and difficulty concentrating.

since moving across to the NSD, my pain threshold has re-adjusted to a more normal level, and I now find paracetamol effective for low level knocks and bumps or headaches...


First Symptoms 1999, Diagnosed 2012. NSD since April 2013, Pain free since July 2013
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Thank you for your answer TheoJones,
how much paracetamol do you take?

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A word of caution about the use of paracetamol. Be very careful about not exceeding the daily dosage.

The real problem of paracetamol is the potential for liver damage. If you exceed the dosage then you risk problems with the liver.

I would add cautions about ibuprofen here but I think most of you know not to have it on an empty stomach because it can cause ulcers.

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It does nothing for my pain. I rather not taking anything then take tylenol (Paracetamol), as to conserve my liver (since I get no relief from it anyway).

This is from my personal experience. Others might actually get some relief; so you have to judge for yourself if you get enough relief from it to warrant it risks.

Meagain is very right. People underestimate it's harmful potential since it's a OTC drug. Even taking slightly above the recommended dosage has the potential to cause permanent liver failure (in fact I believe I read some where that they have decreased the max dosage due to the large potential of harm).

Joined: Jun 2014
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I have nephrotic syndrome of the kidneys. I was losing up to 7 grams of protein thru my urine every day. I am on cyclosporine twice a day to try and save my kidneys. Since being on cyclosporine all of my elevated liver functions have dropped back into the black . It appears I have also been suffering from relatively mild auto-immune hepatitis.My only allowable pain relief has been four panadol osteo a day. They may as well have been suppositories for all the help they are. Unfortunately cyclosporine can be hepa and nephra toxic so I have blood tests all the time. Fortunately I am on a blood pressure drug called diltiazem which allows me to absorb cyclo much much better so I get good results on a much lower dose. My rheumatologist does not care about my AS , he told me to see an orthopaedic specialist. He only cares about the psoriatic arthritis. Between my gp and nephrologist I have tried most of the painkillers including all of the eipilepsy //neurological anaelgesiscs. I have tried norspan (morphine) and fentanyl(an artificial opiate) patches I find patches absolutely hopeless . The dose they deliver is all over the place and I think I have come close to accidental overdoses a couple of times. I am now on slow release oxycodone. Finally I am getting some consistently good pain relief without mad dreams and nightmares. It has taken a long long time to get there. I realise I may become dependant but as long as I don't miss use them I should be ok... Ron.


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