Originally Posted By: jpinperth
Hi

I was just wondering if we have diabetics here who can't tolerate Metformin. I have now tried it twice and both times after two weeks I get feeling down and want to cry all the time. Please let me know if you have had these side effects or know of someone who has.

Thanks,
Janet


I have been on metformin for more than 5 years now and I have never seen any information regarding the symptoms you are stating. I even looked up the side effect on rxlist.com and I don't see any of what you are saying. Your reaction would be something extremely rare. If you are taking other drugs, you may want to check of a drug interaction. Metformin is THE best diabetic drug to be on if you are able to take it. Renal impairment is the main reason why you would not be taking this drug. This drug reduces insulin resistance, can help you lose weight, has been shown prevent cancer, and is listed as an anti-aging drug in some studies. THE one side effect that turns people off to the drug is that it's nickname is metfartin. I can attest to this whole-heartedly. It has a GI effect that can be mild to extreme. I will tell you that if you imbue too many carbs and take this drug, beano will not save you the unpleasantness of the resulting reaction in your gut.