Well, I don't know much but some thoughts do occur to me. I've had A.S. since I was 21 (37 now) and the one thing that really always puzzles me about it is the weird way that pain/inflammation literally moves around my body jumping from place to place. Last Monday to Wednesday I had neck pain, Thursday I had shoulder pain, Friday I had upper back pain, Saturday I had leg pain (one knee and upper thigh) and today I have lower back and sacroilieac pain. My one blessing is that A.S. seems to target one or two areas of my body at a time. But what causes inflammation to move around a body like that? I keep hoping that it will one day just move right on out of my body. I can understand inflammation as a reaction in general but the movement truly puzzles me.
I'm sorry, since this is probably not the response you were hoping for but reading your post made me think and puzzle some more about this.
Ruby