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Joined: Mar 2008
Posts: 3,233
Dow Offline
Imperial_AS_Kicker
Offline
Imperial_AS_Kicker
Joined: Mar 2008
Posts: 3,233
Hi Michelle:

Thanks for all your postings on Apremilast, I will ask my Rheumy about it next week, it will at least be a way to see if he is up on the latest news. Very excited that you are having good results!

Also following the dog sub-thread of this, we have four American Eskimos (well three and a half) and only recently learned that the original name for the breed was German Spitz, renamed after WWII. We call 'em the white monkeys


Dow
Joined: Apr 2002
Posts: 3,607
Offline
Joined: Apr 2002
Posts: 3,607
Wow, Michelle, that is amazing news! I'm so happy for you!

Do they have any update on if/when this will be available to the general public?

Joined: Feb 2006
Posts: 1,483
Silver_AS_Kicker
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Silver_AS_Kicker
Joined: Feb 2006
Posts: 1,483
Cool. Not a huge surprise since it inhibts IL 23 and TNF. This helps confirm the IL 23 connection to me


No families take so little medicine as those of doctors, except those of apothecaries.

Oliver Wendell Holmes
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
OP Offline
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269
Hi Dow, I'm familiar with the German Spitz story, they used to call German Shepherds by the name Alsatian...and I think the name is still used in parts of Europe. The American Eskimo is a beautiful dog! And I like the white monkey nick-name...very cute!


Age 7- Kidney Necrosis
Age 11-Bursitis
Age 14-Costo
Age 17-Psoriasis
Age 32-Thoracic Outlet Syndrome
Age 33-Sacroilitis
Age 35-Interstitial Cystitis
Age 40-AS
Age 44-Fibro
Age 44-PsA
Age 45-MS
Age 46-Sjogrens
Age 46-Raynauds
Age 47-PF
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
OP Offline
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269
Hi Megan, I haven't heard anything about a potential release date, maybe the manufacturers website may have that info, I'll check on that and get back to you on it...


Age 7- Kidney Necrosis
Age 11-Bursitis
Age 14-Costo
Age 17-Psoriasis
Age 32-Thoracic Outlet Syndrome
Age 33-Sacroilitis
Age 35-Interstitial Cystitis
Age 40-AS
Age 44-Fibro
Age 44-PsA
Age 45-MS
Age 46-Sjogrens
Age 46-Raynauds
Age 47-PF
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
OP Offline
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269
Hi Drizz...I couldn't agree with you more and what was it...a little over a year ago that they announced the discovery of the connection between IL-23 and the ARTS1 gene and inflammation? and they had a drug in clinical trials within 6 months?! Boy....we've come a long way! Now if I could just convince my Primary Care Doctor that AS isn't "a men's only" disease!


Age 7- Kidney Necrosis
Age 11-Bursitis
Age 14-Costo
Age 17-Psoriasis
Age 32-Thoracic Outlet Syndrome
Age 33-Sacroilitis
Age 35-Interstitial Cystitis
Age 40-AS
Age 44-Fibro
Age 44-PsA
Age 45-MS
Age 46-Sjogrens
Age 46-Raynauds
Age 47-PF
Joined: Feb 2006
Posts: 1,483
Silver_AS_Kicker
Offline
Silver_AS_Kicker
Joined: Feb 2006
Posts: 1,483
HI Michelle

We got lucky IL23 is associated with more widespread diseases like Crohn's and psoriasis and the drug research was well underway in those areas. We are riding those coattails but that is OK as long as it gets done

Steve


No families take so little medicine as those of doctors, except those of apothecaries.

Oliver Wendell Holmes
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
OP Offline
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269
Yeah Steve, that probably happened when I wasn't looking! I lost faith in new medicines after a miracle cure almost killed me, back in the nineties, had I not already known and trusted the judgement of Cindi and Shondra, I probably wouldn't have participated in their clinical trial....


Age 7- Kidney Necrosis
Age 11-Bursitis
Age 14-Costo
Age 17-Psoriasis
Age 32-Thoracic Outlet Syndrome
Age 33-Sacroilitis
Age 35-Interstitial Cystitis
Age 40-AS
Age 44-Fibro
Age 44-PsA
Age 45-MS
Age 46-Sjogrens
Age 46-Raynauds
Age 47-PF
Joined: Dec 2008
Posts: 718
Decorated_AS_Kicker
Offline
Decorated_AS_Kicker
Joined: Dec 2008
Posts: 718
Thank you for the information.

Jayaram

Joined: Sep 2001
Posts: 8,397
L
Lon Offline
Very_Addicted_to_AS_Kickin
Offline
Very_Addicted_to_AS_Kickin
L
Joined: Sep 2001
Posts: 8,397
My Dear Friend,
I think our police depart. uses the black dog, the Corleone.
I did see two pure white dogs a few months ago in the back of a truck at the gas station. He said they were just a hobby, but they were sure pretty.
How much do they shed?
I am gone some nights. And I am working with convicted felons;so I would like a dog that could come inside and be a comfort to my wife. Yet would be hardy enough to stay out, with shelter of course.
I have enjoyed hearing about your dogs.
Years ago we had a decendant of rin tin tin. But she was so timid, I did not take the time to teach her.....
Thanks again
Lon

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