Like Allen said AS is a slow progressive disease. I forgot to mention that too. Sue thank you for coming up with the stats, that is good to know especially for Al39 to get a correct, Positive or negative. So you have the kind that attacks your body where and when it wants to.
Hmmm gotta think back. The eye twitching started in my early 20's felt real weird, also the same time I was having the tail bone pain. The iritis came on about 5 years after the twitching started and went away when the iritis started. When it hit me it was like a freight train, one day I was fine and the next I thought my eye was coming out. I was Rx'd prednisone drops and antibotics for the "pink eye" they thought I had.
But yes about 5 years after the twitching. But I attributed the twitching/fluttering to nerves.
Sue how long did it take you to get a diagnosis if you don't mind me asking being HLAB27 neg.? You must have had an awesome doctor to figure things out! That is wonderful, horrible Dx but wonderful that they caught it.
Christina
Christina  I may have AS, PsA, ReA, SpA and every Itis you can imagine but my Itis's do not define me. Dx'd April 2008 Prednisone 5mg Plaquinel 400mg Enbrel 50mg/week Methotrexate 25mg/week Lidoderm 5% patch, love em! Bio-35 multivit I call them crackamins their great for energy! and a whole slew of anti-inflammatory and pain pills 
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