Hi John - I take citalopram and have done for many years. Like Kevin, I'm now on a maintenance dose of 10 mg. When my depression was at its worst, it took 60 mg per day to get it under control and that took several months (I was very ill). The lethargy bothered me so much I tried to come off it but the depression was too serious. I had an excellent psychiatrist at the time (I believe psychiatrists are much more knowledgeable about these meds that regular GPs) and she recommended that I reduce the dose of citalopram and add in buproprion which acts on different neurotransmitters and helps to balance out the effect of lethargy from the citalopram while adding further antidepressant capacity.
It worked wonders - I continue to take a blend of the two drugs. The buproprion gave me back the energy and drive that the citalopram had removed.
I now take 100 mg of buproprion daily and 10 mg of citalopram.
