Hello,

I am 23 yr old female, currently on 25 mg/week of MTX injectable. i have AS and also psoriasis. I have been on MTX for about 6 months in total. I began with 12 mg/week (tablet form) with not much result and upped the dosage to 25 mg/week. I was having good results except I couldn't tolerate the nausea so my rheum switched me to the injectable. I had great results for a few months but I feel that it's not working as well. Could also be that I am down from 2000 mg of Naproxen before to about 500 mg Naproxen per day currently.

My suggestion is to try the injectable MTX if you can, it's just a small injection into the fat in your tummy or your thigh. I have no nausea, the only side effects I have had are small sores inside my nose. Pain in the butt.

Good luck to you, truly. Keep with it and have faith!

24 years old, diagnosed with psoriasis at 11, AS at 20, and IBS at 21. HLA B27+. Have tried NSAIDS, oral and injectable MTX. Currently experimenting with diet.

Love the support that this website offers. You are all warriors!