Wendy and Rumble, MTX is
known to cause tiredness. Massive tiredness.
When I was on MTX I could sleep all day and all night - continually tired, wretched feeling, like a washed out toe rag 24/7
Do also know that when on the MTX it took care of a horrible gumboil abscess. When I came off the MTX, the abcess burst - yea: just as I was going in for an MRI... Great timing, what?

Hope you guys can sort problems various.