|
Forums33
Topics44,174
Posts519,810
Members14,038
| |
Most Online1,931
Jan 16th, 2023
|
|
Administrator/owner:
John (Dragonslayer)
Administrator:
Melinda (mig)
WebAdmin:
Timo (Timo)
Administrator:
Brad (wolverinefan)
Moderators:
· Tim (Dotyisle)
· Chelsea (Kiwi)
· Megan (Megan)
· Wendy (WendyR)
· John (Cheerful)
· Chris (fyrfytr187)
|
|
If you want to use this QR code (Quick Response code) just save the image and paste it where you want. You can even print it and use it that way. Coffee cups, T-Shirts etc would all be good for the QR code.
|
|
|
|
Joined: Aug 2003
Posts: 2,717
ironchef
|
ironchef
Joined: Aug 2003
Posts: 2,717 |
|
|
|
|
|
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
|
|
OP
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269 |
Thanks Ben, I'm keeping my fingers crossed that this will be the one! I hope all is well with you, it's always nice to see you when you drop in... 
Age 7- Kidney Necrosis Age 11-Bursitis Age 14-Costo Age 17-Psoriasis Age 32-Thoracic Outlet Syndrome Age 33-Sacroilitis Age 35-Interstitial Cystitis Age 40-AS Age 44-Fibro Age 44-PsA Age 45-MS Age 46-Sjogrens Age 46-Raynauds Age 47-PF  
|
|
|
|
|
Joined: Apr 2002
Posts: 12,465
|
|
Joined: Apr 2002
Posts: 12,465 |
Wow Michelle... this is exciting news! I am so grateful to those who participate in these trials to further the research that has such potential to help our community.
Gee that is one small sample size for AS so far, lol, I hope they'll be able to recruit a few more ASers ... I'd try not to get your hopes up too high though, as most often these trials are blinded, meaning that even your doctor won't know whether you're getting the placebo or not. Errr, but maybe that's not the case for phase II trials???
Yay - it will be so interesting to read your updates and I'll be keeping my fingers crossed that this new med will work wonderfully for you! I heard they've been working furiously on pill versions of these meds and if they have the same positive effects they'll be such a blessing.
So cool that this one targets IL23 + TNFa. 
from Celdene.com:
"Apremilast is a member of a proprietary pipeline of novel small molecules with anti-inflammatory activities that impedes the production of multiple pro-inflammatory mediators by inhibiting PDE4 resulting in reductions in TNF-alpha as well as interleukin-2 (IL-2), IL-17 and IL23, interferon-gamma, leukotrienes, and nitric oxide synthase. Apremilast is our lead investigational drug in this class of anti-inflammatory compounds. Based on promising results from proof-of-mechanism and clinical studies, Celgene is accelerating clinical and regulatory strategies for apremilast in psoriasis and psoriatic arthritis, as well as embarking on exploratory clinical trials in rheumatoid arthritis and additional rheumatic, dermatologic and inflammatory diseases to determine the potential of apremilast across a broad range of debilitating inflammatory diseases."
Hugs and best of luck!!
mig
Last edited by mig; 09/26/08 05:18 PM.
|
|
|
|
|
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
|
|
OP
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269 |
Hey Mig, I just called the doctor's office, Shondra was gone for the day but her assistant answered the phone so I asked her if it was a blind or double-blind study and she said that she didn't think it was either....I hope she's right but I will find out everything Tuesday... 
Age 7- Kidney Necrosis Age 11-Bursitis Age 14-Costo Age 17-Psoriasis Age 32-Thoracic Outlet Syndrome Age 33-Sacroilitis Age 35-Interstitial Cystitis Age 40-AS Age 44-Fibro Age 44-PsA Age 45-MS Age 46-Sjogrens Age 46-Raynauds Age 47-PF
|
|
|
|
|
Joined: Apr 2002
Posts: 12,465
|
|
Joined: Apr 2002
Posts: 12,465 |
Oh wow that is great for you Michelle!!!  And thanks for checking for me.  I was rather curious to know. More hugs, mig
|
|
|
|
|
Joined: Nov 2001
Posts: 18,186 Likes: 7
Very_Addicted_to_AS_Kickin
|
|
Very_Addicted_to_AS_Kickin
Joined: Nov 2001
Posts: 18,186 Likes: 7 |
Michelle!!!! I'm keeping my fingers crossed for you!! Please do keep us posted.
Warm hugs,
Kat
A life lived in fear is a life half lived.
"Strictly Ballroom"
|
|
|
|
|
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
|
|
OP
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269 |
Well, I'm not totally sure yet Mig but I'm so hoping that she's right! But even if it is a blind study, my chances of getting the drug are way better than if I don't participate at all....
Age 7- Kidney Necrosis Age 11-Bursitis Age 14-Costo Age 17-Psoriasis Age 32-Thoracic Outlet Syndrome Age 33-Sacroilitis Age 35-Interstitial Cystitis Age 40-AS Age 44-Fibro Age 44-PsA Age 45-MS Age 46-Sjogrens Age 46-Raynauds Age 47-PF
|
|
|
|
|
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
|
|
OP
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269 |
Hey Kat...I will keep yall posted and I'm going to share every bit of information that I'm legally allowed to on this....
Age 7- Kidney Necrosis Age 11-Bursitis Age 14-Costo Age 17-Psoriasis Age 32-Thoracic Outlet Syndrome Age 33-Sacroilitis Age 35-Interstitial Cystitis Age 40-AS Age 44-Fibro Age 44-PsA Age 45-MS Age 46-Sjogrens Age 46-Raynauds Age 47-PF
|
|
|
|
|
Joined: Apr 2008
Posts: 386
Fifth_Degree_AS_Kicker
|
|
Fifth_Degree_AS_Kicker
Joined: Apr 2008
Posts: 386 |
How cool! I can't wait to hear your updates!
|
|
|
|
|
Joined: Nov 2007
Posts: 6,269
Addicted_to_AS_Kickin
|
|
OP
Addicted_to_AS_Kickin
Joined: Nov 2007
Posts: 6,269 |
Thanks Gardengirl, I'm pretty excited about it....it will be wonderful if it works!!
Age 7- Kidney Necrosis Age 11-Bursitis Age 14-Costo Age 17-Psoriasis Age 32-Thoracic Outlet Syndrome Age 33-Sacroilitis Age 35-Interstitial Cystitis Age 40-AS Age 44-Fibro Age 44-PsA Age 45-MS Age 46-Sjogrens Age 46-Raynauds Age 47-PF
|
|
|
|
0 members (),
89
guests, and
64
robots. |
|
Key:
Admin,
Global Mod,
Mod
|
|
|
|
