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Joined: Sep 2001
Posts: 2,364
Colonel_AS_Kicker
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Colonel_AS_Kicker
Joined: Sep 2001
Posts: 2,364 |
I'm not sure whether this was reported here before, but this is the only study I have seen of the use of antibiotics to treat AS. It might be of interest to those thinking of using antibiotics in conjunction with diet.
1: South Med J. 2007 Apr;100(4):366-70. Links
Treatment of ankylosing spondylitis with moxifloxacin.Ogrendik M.
Division of Rheumatology, Nazilli State Hospital, Turkey. porphyromonas@superonline.com
Ankylosing spondylitis (AS) is a human leukocyte antigen (HLA)-B27-associated chronic inflammatory disease of unknown etiology. There are few effective treatments for ankylosing spondylitis, which causes substantial morbidity. The relationship between AS and enterobacteria, especially Klebsiella pneumoniae, has been reported from several groups in several countries. We performed an open-label trial of moxifloxacin, a fluoroquinolone antibiotic, in patients with ankylosing spondylitis. Treatment with moxifloxacin resulted in significant and sustained improvement. At 12 weeks, patients treated with moxifloxacin had significantly greater improvement in primary outcome measures (P < 0.001). The moxifloxacin group also had significantly greater improvement in many of the secondary outcome measures (P < 0.001). In this twelve-week trial, moxifloxacin was safe, well tolerated, and associated with improvement in the inflammatory symptoms of AS.
PMID: 17458395 [PubMed - indexed for MEDLINE]
Last edited by bilko; 11/30/07 10:21 AM.
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Joined: Oct 2006
Posts: 2,001
Major_AS_Kicker
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Major_AS_Kicker
Joined: Oct 2006
Posts: 2,001 |
Interesting. Thanks for posting this.
I've been trying to decide whether to pursue antibiotic therapy myself.
Karen
I cannot make the universe obey me. I cannot make other people conform to my own whims and fancies. I cannot make even my own body obey me.
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Emily Dickinson
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