I take probiotics typically away from large meals. When taken with meals the bacteria may assist with digestion.
I prefer to try and heal the intestines, so take away from meals. Presently I drink kefir first thing in morning or eat some sauerkraut away from meals. I do this 5-6 times typically a week.. should do more, but so busy forget at times.
If they do not bother you.. can do each morning and evening if want to be aggressive (but not with hot tea/coffee) as the hot liquid may also kill the bacteria I have read.
AS may win some battles, but I will win the war.
KONK - Keep ON Kicking