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#520023 - 02/01/20 08:47 AM Fecal Microbiota Signature in the Patients With AS
MollyC1i Offline
Very_Addicted_to_AS_Kickin

Registered: 01/21/04
Posts: 9833
Loc: Brittany, France (since Nov 08...
https://www.healio.com/rheumatology/spondyloarthropathies/news/online/%7B47729d65-828c-4471-83d5-ec097ab7508a%7D/patients-with-ankylosing-spondylitis-display-distinct-fecal-microbiota-signature

“We have demonstrated a distinct fecal microbiota signature in the patients with AS, which differed from the patients with UC and healthy controls,” Klingberg and colleagues wrote. “In the AS patients, fecal microbiota signature was linked to fecal calprotectin levels, a marker of intestinal inflammation, but not to other clinical parameters. This suggests that the intestinal microbiota may be involved in an interplay with subclinical gut inflammation in AS.” – by Jason Laday

cat
_________________________
MollyC1i - Riding OutAS

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#520037 - 02/12/20 09:49 AM Re: Fecal Microbiota Signature in the Patients With AS [Re: MollyC1i]
pspondylitis Offline
Journeyman_AS_Kicker

Registered: 03/18/12
Posts: 122
The big question is the chicken and egg question .... which came first. Is it the damaged gut that causes certain bugs to grow or is it certain bugs that then damage the gut.
_________________________
Age 52. Psoriatic spondylitis. HLA B27 negative. MRI negative.

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#520068 - 03/02/20 08:53 AM Re: Fecal Microbiota Signature in the Patients With AS [Re: MollyC1i]
EricaK Offline
Royal_AS_kicker

Registered: 06/23/10
Posts: 3854
Loc: Colorado, USA
My husband had hip replacement surgery last August and the antibiotics & surgical chemicals severely damaged his overall health. I know that sounds alarmist, but he was always superbly healthy before that pre-surgical antiobiotic wash, betadine caused infection (because he's allergic to shrimp and they used betadine anyway), and antibiotics to get rid of the betadine caused infection. Since then he's had a horrible sinus infection which required more antibiotics and 3 days off work, and now he's still got the cough - 7 weeks later. Uff... I don't know if he'll have the other hip replaced. And here's a weird note - since the antiobiotics he doesn't smell the same. He used to always smell like a combination of cookies & bacon, and now he smells bland. Also, when he poops there is zero smell in the bathroom. Crazy right? Anyhow - we are both taking broad spectrum probiotics to try and rectify the situation.
_________________________
ANA+ RF+ Rh- HLAB27+
Dx JRA 1967, GAD 1997, AS 2009, HMs 2010, CPS 2013
pulmonary edema w/ NSAIDS 2009

Movin' it so I don't lose it!


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