How is nonradiographic axial spondyloarthritis distinguished from radiographic disease -- and how do management strategies differ?
Nonradiographic Axial Spondyloarthritis
Clinical and Therapeutic Relevance
Nilasha Ghosh; Eric M. Ruderman
DISCLOSURES Arthritis Res Ther. 2017;19(286)
Abstract and Introduction
Current classification criteria for axial spondyloarthritis (axSpA) provide for the inclusion of patients with a wide range of presentations and manifestations. While not considered a formal subclassification, patients are often divided into radiographic or nonradiographic axSpA based on the presence or absence of radiographic sacroiliitis. This review will focus on nonradiographic axSpA and will discuss clinical manifestations of disease that distinguish, or in many cases do not distinguish, this entity from other individuals with axSpA. This review will also cover treatment paradigms for nonradiographic axSpA, particularly the use of biologic therapies, where current data suggest that nonradiographic disease should be managed largely the same as radiographic disease, or classical ankylosing spondylitis."
(snip...) Search Strategy
"Information for the review has been drawn from manuscripts in the PubMed database published within the last 10 years. Search terms included "axial spondyloarthritis," "non-radiographic axial spondyloarthritis," "criteria AND axial spondyloarthritis," "inflammatory spinal disease," "[TNF inhibitors OR treatment] of axial spondyloarthritis," "biomarkers AND axial spondyloarthritis," "[predictors OR progression] of axial spondyloarthritis," "fibromyalgia AND axial spondyloarthritis," "therapy + axial spondyloarthritis" and "monitoring tools AND disease activity."
We've come a long way... !!
Keeping on, Keeping on - Yea