Mechanism regulating gene expression linked to bone and joint damage in ankylosing spondylitis
Posted: 12 Jun 2015 06:18 AM PDT
A new study reveals that DNA methylation -- a mechanism that regulates gene expression -- could influence the progression of structural damage to the joints and spine in ankylosing spondylitis. Study findings showed significant associations between a low methylation score and more radiographic progression of the disease, and implicated smoking in worsening of disease outcome.

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