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#500713 - 02/16/14 02:11 PM Re: Anyone use diclofenac? [Re: Sue22]
MSK Offline
Apprentice_AS_Kicker

Registered: 11/04/12
Posts: 97
Loc: Turkey
Originally Posted By: Sue22
Not orally, but I use flector patches, which are dichlofenac, over my SI joint.

I'm on Humira, but my SI joint still needs a bit of help, maybe due to the damage caused over the years by the inflammation, anyway over the SI joint, changed every 12 hours, it helps.

I started doing that because NSAIDs tend to give me edema and/or gastritis, or they are too mild to do much good at all, but the one's strong enough to help, give me the side effects, if taken internally (I've tried almost 10 of them, a dozen if you count the cox2 inhibitors (celebrex, vioxx when it was on the market…both gave me side effects).



Sue, are you sure using NSAIDS externally has less side effects (or no side effects) than oral usage? If i can recall correctly, when it is active in blood, it thins off the gi tract, making it succeptiple to germ or acid. The way it gets into blood system is irrelevant, i thought?
_________________________
Diagnosed at July 2012 after 8 months of pain. HLA-B27 negative.
NSAIDS don't really work. I can't use Anti-TNF because i had tuberculosis years ago.
Wish you all best health, M. Sami Kuzey

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#500715 - 02/16/14 04:27 PM Re: Anyone use diclofenac? [Re: MSK]
Sue22 Offline
Very_Addicted_to_AS_Kickin

Registered: 01/13/08
Posts: 21346
Loc: Upstate NY
Originally Posted By: MSK
Originally Posted By: Sue22
Not orally, but I use flector patches, which are dichlofenac, over my SI joint.

I'm on Humira, but my SI joint still needs a bit of help, maybe due to the damage caused over the years by the inflammation, anyway over the SI joint, changed every 12 hours, it helps.

I started doing that because NSAIDs tend to give me edema and/or gastritis, or they are too mild to do much good at all, but the one's strong enough to help, give me the side effects, if taken internally (I've tried almost 10 of them, a dozen if you count the cox2 inhibitors (celebrex, vioxx when it was on the market…both gave me side effects).



Sue, are you sure using NSAIDS externally has less side effects (or no side effects) than oral usage? If i can recall correctly, when it is active in blood, it thins off the gi tract, making it succeptiple to germ or acid. The way it gets into blood system is irrelevant, i thought?


I don't know how much is getting into my blood stream. I just know it helps my SI and I haven't had any side effects from it that I can tell. Maybe its a matter of how much gets in?
_________________________

sue

Spondyloarthropathy, HLAB27 negative
Humira (still methylprednisone for flares, just not as often. Aleve if needed, rarely.)
LDN/zanaflex/flector patches over SI/ice
vits C, D. probiotics. hyaluronic acid. CoQ, Mg, Ca, K.
chiro
walk, bike
no dairy (casein sensitivity), limited eggs, limited yeast (bread)

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#500719 - 02/16/14 06:23 PM Re: Anyone use diclofenac? [Re: Bax1]
Wilhelm Offline
First_Degree_AS_Kicker

Registered: 10/02/12
Posts: 190
I was on diclofenac for more or less a year before I developed abdominal pain intense enough to make me roll up in a ball. I stopped them and I'm ok now.

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#500723 - 02/16/14 08:14 PM Re: Anyone use diclofenac? [Re: Bax1]
Tnate Offline
Fifth_Degree_AS_Kicker

Registered: 10/06/08
Posts: 360
Loc: South Florida
Np just read that crp should only be used as a baseline by reveille. Never saw it in the lit or heard it before but it makes perfect sense. Hopefully I won't need his help by the time I get there but he's my hero so I'm going either way and this whole NSAID thing is a big reason why or In case humira isn't enough for my disease by 12 weeks.

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#500724 - 02/16/14 08:16 PM Re: Anyone use diclofenac? [Re: Bax1]
Tnate Offline
Fifth_Degree_AS_Kicker

Registered: 10/06/08
Posts: 360
Loc: South Florida
It was novel as far as I know* about crp

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#502346 - 04/10/14 01:43 AM Re: Anyone use diclofenac? [Re: Bax1]
sammiejo Offline
New_Member

Registered: 04/09/14
Posts: 2
I was prescribed Diclofenac and got awful stomach pains after a while. The doctor then suggested I come off it and gave me Omeprazole to calm the stomach down, which it eventually did after about 8 weeks. I tried taking them again with the Omeprazole but pains came back. The doctor then switched me to Celebrex which is supposed to have a better effect on the stomach, but after a while it came back on this and did nothing any more for the AS pain/. Can't take NSAIDs any more so switched to Humira which has to be prescribed in the UK. Only had 3 jabs but things seem to have improved.

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#502347 - 04/10/14 02:19 AM Re: Anyone use diclofenac? [Re: Bax1]
MollyC1i Offline
Very_Addicted_to_AS_Kickin

Registered: 01/21/04
Posts: 9842
Loc: Brittany, France (since Nov 08...
sammiejo - I had the same problem with NSAIDs, and this in spite of taking a stomach protector. Celebrex was my med of choice until it started giving me horrific GERD/Reflux. Had to stop it. Then went on to low dose Naltrexone and low starch diet. This has worked pretty good for me. I don't take the biggie biotherapies, have Actinic Keratosis and have been warned that the bios 'could' cause full blown skin cancer... I aint opening any doors like that thanks !
_________________________
MollyC1i - Riding OutAS

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