banners
Kickas Main Page | Rights and Responsibilities | Donate to Kickas
Kickas Links
·HOME
·Forums Main Index
·Register!
MEDICAL CENTRE
·Medicine Contract
·AS Patient Guidebook
·Pain Map
·Disease Modification
·Ask your doctor
·AS and RA Papers
·AS Acronyms
DIET CENTRE
·London AS Diet
·Molecular Mimicry
·AS Dietary Primer
·AS Food Guide
SUPPORT CENTRE
·In Memorium
·KickAS Stories
·KickAS Banners
·Donations
Forum Stats
12,630 Registered Members
28 Forums
43,330 Topics
515,614 Posts

Most users ever online: 1,568 @ 06/29/16 03:25 PM
Newest Members
yurayurayura, Foonda, Dea, Navdeep, dwarner
12630 Registered Users
KickAs Team
Administrator/owner:
John (Dragonslayer)
Administrator:
Melinda (mig)
WebAdmin:
Timo (Timo)
Administrator:
Brad (wolverinefan)

Moderators:
- Tim (Dotyisle)
- Chelsea (Kiwi)
- Megan (Megan)
- Wendy (WendyR)
- John (Cheerful)
- Chris (fyrfytr187)

QR Code
If you want to use this QR code (Quick Response code) just save the image and paste it where you want. You can even print it and use it that way. Coffee cups, T-Shirts etc would all be good for the QR code.
Topic Options
#484053 - 02/23/13 12:44 PM Does low GFR mean kidney disease?
Dizzydi Offline
New_Member

Registered: 02/22/13
Posts: 4
Hi there, I am a newbie,

Also thank you for giving me the opportinity to join a wonderful helpful site, much appreciated.

What I want to know it if possible please, if low gfr always mean kidney disease? or could it mean another health condition that can cause the functioning of the GFR to drop?

Thank you in advance?

Top
#484054 - 02/23/13 12:59 PM Re: Does low GFR mean kidney disease? [Re: Dizzydi]
Possi Offline
Addicted_to_AS_Kickin

Registered: 11/13/02
Posts: 6913
Loc: Oklahoma where the wind comes...
Welcome Dizzydi,

This is a wonderful site with great friendly informed people.
I am not going to try to answer your question. :o) Just want to welcome you.

Come back often.

Possi
_________________________


Possi
*********************************************************

RUN WHEN YOU CAN,
WALK IF YOU HAVE TO,
CRAWL IF YOU MUST,
JUST NEVER EVER GIVE UP!



"A FRIEND HEARS THE SONG IN YOUR HEART AND SINGS IT TO YOU WHEN YOU CAN'T REMEMBER THE WORDS."

"A FRIEND LOOKS THROUGH YOUR BROKEN FENCE TO ADMIRE YOUR FLOWERS."


Top
#484055 - 02/23/13 01:06 PM Re: Does low GFR mean kidney disease? [Re: Possi]
Dizzydi Offline
New_Member

Registered: 02/22/13
Posts: 4
Hi Possi

And thank you. It's a wonderful site. x

I am from the UK ;-)


Edited by Dizzydi (02/23/13 01:07 PM)

Top
#484061 - 02/23/13 02:13 PM Re: Does low GFR mean kidney disease? [Re: Dizzydi]
cemc Offline
Major_AS_Kicker

Registered: 01/25/10
Posts: 2105
Loc: UK
How low is your eGFR? Mine hovers between 55 and 65, which is a bit odd as it usually is meant to just do a slow decrease rather than go up and down like mine does. My doctor isn't concerned right now because I don't have obvious protein in my urine. Chronic kidney disease (CKD) is actually very common. It would seem that once it gets to 60 or below in the Uk they start to monitor you with regular blood tests (though mine are only once a year), and if it drops more than 5 points a year they would look at it more seriously. Also if you show protein regularly in your urine. You don't even get referred to renal specialists here unless you have a specific disease that might be affecting your kidneys (and I think lupus is probably the only rheumatology one they consider significant) or eGFR gets down to about 45 I think.

Ask your GP about it though, and ask how often they are going to monitor it, and get them to check your blood pressure.

I think the answer to your question "does a low eGFR always mean kidney disease" is yes, but that doesn't mean its significant, or that there is a definite reason for it, or that it needs treating, though once its noticed your GP should regularly check things like blood pressure etc and monitor it.

Note that my answer comes from my experience in the UK, and you'd possibly get quite a different answer about investigations for CKD in the US or another country.

Top
#484067 - 02/23/13 04:01 PM Re: Does low GFR mean kidney disease? [Re: cemc]
Dizzydi Offline
New_Member

Registered: 02/22/13
Posts: 4
Originally Posted By: cemc
How low is your eGFR? Mine hovers between 55 and 65, which is a bit odd as it usually is meant to just do a slow decrease rather than go up and down like mine does. My doctor isn't concerned right now because I don't have obvious protein in my urine. Chronic kidney disease (CKD) is actually very common. It would seem that once it gets to 60 or below in the Uk they start to monitor you with regular blood tests (though mine are only once a year), and if it drops more than 5 points a year they would look at it more seriously. Also if you show protein regularly in your urine. You don't even get referred to renal specialists here unless you have a specific disease that might be affecting your kidneys (and I think lupus is probably the only rheumatology one they consider significant) or eGFR gets down to about 45 I think.

Ask your GP about it though, and ask how often they are going to monitor it, and get them to check your blood pressure.

I think the answer to your question "does a low eGFR always mean kidney disease" is yes, but that doesn't mean its significant, or that there is a definite reason for it, or that it needs treating, though once its noticed your GP should regularly check things like blood pressure etc and monitor it.

Note that my answer comes from my experience in the UK, and you'd possibly get quite a different answer about investigations for CKD in the US or another country.



Thank you for your input.
I am also in the UK.

The last 3 tests since last May 2012 - 52, then Nov 50, last week recorded at 51, this test was done last Monday 18th Feb 2013 was 51GFR, and my GP is referring me to a Nephrologist, although the list is rather long it can take up to about November before I get to see one.

I am 44 years old (white female), on meds for high bp for the last 10 years just over and recently for cholesterol.

My GP said that I will be checked 3 to 6 months to be kept monitored, but to keep my BP in control.

I have also cut out salts, and drink more water, as I was never much of a water drinker until recent.

Urine tests normal.


Edited by Dizzydi (02/23/13 04:02 PM)

Top
#484090 - 02/24/13 02:15 AM Re: Does low GFR mean kidney disease? [Re: Dizzydi]
rumble Offline
Supreme_AS_Kicker

Registered: 01/31/09
Posts: 4475
Loc: NE Oklahoma
It is tied to the creatinine measurement and your age/sex/race. Whatever affects your creatinine will affect your GFR. That's the short answer. Ask your doc if he/she can answer this question in light of YOUR creatinine. Here is some info from a good source. Keep this site bookmarked because it gives great information on many, many lab tests. (from your friendly neighborhood medical technologist)

eGFR information
_________________________
DX: Psoriatic Arthritis, Osteoporosis, Psoriasis
Meds: MTX since Oct 2009, 15mg/week. Cosentyx (6th biologic) starting soon.
Epidural Steroid Injections x7; Lumbar Radiofreq Ablation x2
SIJ Steroid Injection x3; Bilateral Radiofreq Ablation SIJ x8

Top
#484096 - 02/24/13 07:05 AM Re: Does low GFR mean kidney disease? [Re: rumble]
Dizzydi Offline
New_Member

Registered: 02/22/13
Posts: 4
Hi Rumble and thank you.

Yes it is tied to creatinine measurement
With being new to this sort of thing as well, I find it confusing, but getting there I think.
There was some improvement on the creatinine last week but stil not enough.
I shall have to get hold of the information in front of me to see what is what, but was told my last reading of gfr was 51, a rise of 1% not a lot but better thsn decreasing I suppose.

Can kidney infections also affect creatnine levels, sorry for the questions.

Thank you.

Top
#484117 - 02/24/13 03:03 PM Re: Does low GFR mean kidney disease? [Re: Dizzydi]
cemc Offline
Major_AS_Kicker

Registered: 01/25/10
Posts: 2105
Loc: UK
Glad you have been referred to a nephrologist, though sorry that the waiting list is long. I know I haven't got a show of being referred to anyone until my eGFR gets well below 50.

One thing that you could probably ask about, is if they are going to do a biopsy. If they do one, then make sure they know that you have AS, and ask them if they are going to check for and rule out amyloidosis. It requires special stains to look for it, and because its rare they might not think about it, but secondary amyloidosis is a recognised rare complication of uncontrolled inflammation. If you did happen to have secondary amyloidosis then its all the more important to get your inflammation under control, and once that happens there is a possibility your kidney function would even improve a bit. Amyloidosis also requires referral to the National Amyloidosis Centre in London for proper management. Just be aware if you google it, that the rather poor prognosis they talk about is for primary amyloidosis, not secondary. Secondary is much more controllable.

FWIW I am pretty convinced that my kidney function is related to inflammation - it actually got a whole lot better during the time I was taking regular NSAIDs and my inflammation wasn't too badly under control, then got worse again when I had to stop taking them. That doesn't exactly fit with the usual assumption that NSAIDs and pain meds can damage your kidneys.

Top

Who's Online
1 registered (1 invisible), 158 Guests and 4 Spiders online.
Key: Admin, Global Mod, Mod
Recent Posts
Has anyone here had C. diff?
by MikeGinnyMD
07/17/17 09:10 AM
No sugar , No starch, say what?
by Amiron
07/17/17 04:15 AM
Pain relief
by Josh300788
07/16/17 02:26 PM
Radon Therapy Czech Republic
by Luigi
07/16/17 07:04 AM
Not getting notifications...
by EricaK
07/12/17 03:46 PM
Multiple Sclerosis link to Prof Ebringer & opinion
by DragonSlayer
07/10/17 03:48 PM
Going to start Cosentyx next--6th biologic
by rumble
07/09/17 02:05 AM
(Views)Popular Topics
"FITNESS" TEAM! - All Physical Activity & Sports 33,460,365
hmmm 1,655,219
Has anyone had Pedicle subtraction Osteotomy ? 1,430,571
What to do about healthcare? Can it be fixed? 915,766
User names revisited 805,578
Medicinal Marijuana 715,146
A.S and beds, What do you find best? 706,898
OMG!!!! 659,128
No/Low Starch Diet Success Stories 490,059
THE STARCH CONTENT OF FOODS - THE LIST 410,169