thanks
Moll
SLJC
Cemc

i notice Moll says that LDN is NOT a painkiller.......but would easing the inflammation not somehow ease the pain?

John : No, LDN is not a pain killer per se, but it does control inflammation. Also, helps enormously with enthesisis - as Sue will chime in with - when she is around. (She might be away for the w'end?) So, in a much as that is what LDN does, then yes, it will control some pain! (IF that sounds like an Irish arguement/discussion, then <LOL>)

Of course, by controlling inflammation, then the LDN is 'also' controlling the AS progressive factors.

Know that I (and many others) are delighted with LDN. An additional factor in the LDN favour, is basically no side effects - for 'most' people.

http://www.gasdetection.com/Interscan_News/health_news_digest210.html

Low Dose Naltrexone - The Next Miracle Drug (2009)

(Sort of useful - just put up on the LDN yahoo group)

Hi John,

Looks like Molly's got you covered! better than I would have; thanks for linking those ebooks molly!

I've been taking it since sept 2009, almost 3 years now

I first got 1.5 mg pills scripted for 3x a day so i could start at 1.5 mg at bedtime, then after a week or two went to 3.0 mg at bedtime, and again 1-2 weeks later went to 4.5 mg at bedtime and have been at 4.5 mg since.

Initially i tried taking it at bedtime, but i have a bad habit of falling asleep in the recliner, waking in the morning, and then taking my drugs and supplements in the morning instead. Sometimes its even later if i get busy and don't get around to taking my meds and supplements when i mean to.

And for me, it doesn't really seem to matter when i take it. of course maybe if i was on a better schedule it would work even better, who knows, but really, i just take it once a day when i get around to it and its all good.

Prior to LDN tore too many tendons and ligaments (the enthesitis that molly mentioned), after LDN, no tears and not even much tendonitis. Its worked fabulously for this symptom (enthesitis).

Also, for me, it doesn't seem to prevent the inflammation as much as helping my body get rid of it. Like if I'm on my feet too much, they'll get really inflamed and sore, but by the next day or two they're nearly better. That kind of recovery NEVER happened before LDN. Same if I overuse my hands.

But I do still flare, so as the books said its not the end all and be all, but it helps me tremendously. But since I flare every few months, a week of methylpred taper seems to take care of that problem.

Additionally the rheumy has me on a number of supplements (see below my name).

All I know is with everything combined, I'm much better now than I used to be. And the LDN is a big part of that (i started it by itself so i could tell).

And I never noticed any side effects from the LDN. Vivid dreaming? Maybe. But i think i had that before the LDN; i think my crazy dreams that wake me just as i'm starting to doze off are from the zanaflex, but that's another discussion.

And as cemc stated, not all doctors will prescribe, but the literature (and others here) can (and did) tell you how to go about it. I took that advice and had my local compounding pharmacy help me figure it out.

Good Luck with the LDN!