Clear links found between inflammation, bacterial communities and cancer (August 16, 2012) -- In a study with inflammation-prone mice, researchers have found a mechanism for the development of colorectal cancer wherein inflammation fosters a change in the gut microbiome including reduced bacterial diversity but also the increased presence of E. coli and related pathogens
. Further mouse studies show genes carried by an E. coli variant can cause cancer development. The suspect bacterial genes are found in a high percentage of human colorectal cancer patients. ... > full storyhttp://www.sciencedaily.com/releases/2012/08/120816141527.htm(snip...)
"it should come as no surprise that a significant disturbance in the human body can profoundly alter the makeup of otherwise stable microbial communities co-existing within it and that changes in the internal ecology known as the human microbiome can result in unexpected and drastic consequences for human health.
A report published in the August 16 online edition of the journal Science gives evidence for such a chain reaction. It has long been known that gut inflammation is a risk factor for cancer. The new study suggests that this may be in part because inflammation disturbs gut ecosystems leading to conditions that allow pathogens to invade the gut. These pathogens may damage host cells increasing the risk of the development of colorectal cancer." (more...)