Just a curious question I have about biologics, in particular humira. I came down with a bad flu type sickness and chose not to take my humira dose which was due at the time. I went a week without taking it and remarkably felt better than I had the whole time I had been on it. Is it possible that humira can make you worse? I injected myself tonight after feeling reasonably good and noticed an instant and significant increase in pain. I'm not sure if I'm imaging things or this is even possible, but could it be making me worse? The reaction literally has put me into a full flare. I can't seem to think what else would cause a reaction like that..

Hi


I can't take them, they all caused me extreme joint and muscle pain. They also caused me insomnia. My Rheumy says it is rare but obviusly happening to me . I stay clear of them.

Gook Luck,
Janet

I just take Omega 3 fish oil for inflammation and tylenol.

Is there any chance you are reacting to one of the ingredients in it rather than the drug itself?

Something to talk to your rheumy about anyway.

I think you should talk to your dr. I didn't do well at all with Humira. It made me really sick and made my bp drop to 42/28. The Humira people contacted me after my first injection and asked me how I did. When I told them, they asked permission to call me dr. and I gave it. He called within a few minutes and told me to NOT take another injection. I think you could call the Humira people and talk to a nurse and she would tell you if this is a reaction.

Take care of yourself.

Blessings.
Possi

Seb,

You might have caught a cold or virus after your last injection in which you need to be off of then until you are over the virus.

It could have been a reaction as well. You might need to take a steroid prior. These TNF blockers have live dna in them-Mouse DNA. Ask your Dr. what to do.

This may or may not have anything to do with what is happening but maybe food for thought.

When ever I get sick as in a cold or flu, tummy bug etc my pain levels seem to reduce. I have been told this is because your immune system is busy fighting the illness and lays off attacking your body for a while. Then when I am over the illness, pain levels increase quite rapidly and are worse than they were before getting sick.

It could be that this is what you are experiencing and especialy if you have stopped the injection for that week.

I would still say check with your doctor because it could be a reaction, you just never know.

not to say it couldn't be a reaction, but the reason my doctor and i decided i'd do humira when or if the time comes is because its not from mouse, but rather its made from a human monoclonal antibody, thus one is less likely to have an "allergic" reaction.

http://en.wikipedia.org/wiki/Adalimumab



not to say one can't still have a reaction, but it would be different......

i took enbrel for a few months and it pretty suddenly started making me feel really awful.. like i was in a constant flare. i stopped taking it, went on no starch diet and am starting to feel really good.
best of luck to you!