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#471514 - 06/10/12 12:26 PM Anti-TNFs - 75% Increased Risk of Shingles
MollyC1i Offline
Very_Addicted_to_AS_Kickin

Registered: 01/21/04
Posts: 8616
Loc: Brittany, France (since Nov 08...
http://www.eular.org/congresspressreleas...ti-tnfs.pdf.pdf

EULAR 2012
Annual Congress of the European League
Against Rheumatism
Berlin, Germany, 6-9 June 2012
TREATMENT WITH ANTI-TNFS CAN INCREASE THE RISK OF DEVELOPING
SHINGLES BY UP TO 75% COMPARED TO MORE TRADITIONAL DRUGS
Results of a systematic review urge prophylactic treatment for those at risk
...(more...)

cat
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MollyC1i - Riding OutAS

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#471516 - 06/10/12 12:50 PM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
Pea Offline
Gold_AS_Kicker

Registered: 02/24/11
Posts: 1542
Loc: Pacific Northwest
That's true, any virus we are susceptible to with a lowered immune system. You are darned if you do and darned if you don't sometimes. I will have to read this article. We can't have any live virus shots either like a flu shot or such.
_________________________
Pea
Diagnosed with A.S. 26 year's ago.
Diagnosed with Fibro 9 year's ago.
Sulphasalazine, Folic Acid, Remicade

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#471519 - 06/10/12 01:15 PM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
MollyC1i Offline
Very_Addicted_to_AS_Kickin

Registered: 01/21/04
Posts: 8616
Loc: Brittany, France (since Nov 08...
It's only a poster presentation, not that much info. EULAR just had their last day of international conference - Germany this time. Sometimes I really do find it seems to be a case of a 'paper, article', at any cost!
_________________________
MollyC1i - Riding OutAS

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#471540 - 06/10/12 06:05 PM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
drizzit Offline
Silver_AS_Kicker

Registered: 02/25/06
Posts: 1416
Loc: Montana
yep

but if my odds of getting shingles are 1 in one hundred and they go to 2 in one hundred that is a 100% increase yet still very low odds. Those percentage numbers can be scary until you break them down a bit.

BTW the shingles vaccine is a live virus and probably should not be taken by anyone on a TNF drug

Pea the flu shot is not a live virus and is OK to take. The nasal spray is a live virus and is to be avoided.


Edited by drizzit (06/10/12 06:07 PM)
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No families take so little medicine as those of doctors, except those of apothecaries.

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#471580 - 06/11/12 11:30 AM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
Pea Offline
Gold_AS_Kicker

Registered: 02/24/11
Posts: 1542
Loc: Pacific Northwest
I heard that to Drizzit but I talked to the Pharmacist an he said no, it is live and he won't give it to me :\
_________________________
Pea
Diagnosed with A.S. 26 year's ago.
Diagnosed with Fibro 9 year's ago.
Sulphasalazine, Folic Acid, Remicade

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#471623 - 06/12/12 02:02 AM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
rumble Offline
Royal_AS_kicker

Registered: 01/31/09
Posts: 3785
Loc: NE Oklahoma
I have to take a flu shot every year for work (hospital) and it is not a live virus vaccine. Like Drizzit says, the Flumist (nasal vaccine) IS a live virus and is contraindicated in people on immune suppressants.

Might be that the pharmacist only had the Flumist available to him since he might not be approved to give injections. I saw the sign up in my pharmacy that they were approved to give the Flumist, but nothing indicating they were able to give injections.
_________________________

DX: psoriatic arthritis, osteoporosis, DDD, psoriasis
Meds: MTX since Oct 2009, 15mg/week--Started Humira March 2013
Epidural steroid injections x4; Lumbar radiofreq ablation
SIJ steroid injection and bilateral radiofreq ablation x4

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#471628 - 06/12/12 04:08 AM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: Pea]
Sue22 Offline
Very_Addicted_to_AS_Kickin

Registered: 01/13/08
Posts: 19064
Loc: Upstate NY
if i remember correctly, my old rheumy office used to encourage, and give flu vaccines to their patients on the biologics, so that they would be less likely to contract the flu. with the reasoning, better to not get an infection (bacterial or viral) while on the biologics.

hadn't thought about the attenuated vs inactivated vaccines. so thanks for that information. smile


Edited by Sue22 (06/12/12 04:08 AM)
_________________________


sue

USpA
LDN/zanaflex/flector
vits C, D. probiotics. fish oil. CoQ, Mg, Ca
pred taper for flares
occasional naproxen / Aleve
chiro
walk
no dairy (casein sensitivity), limited eggs
future: humira, soon I hope

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#471687 - 06/13/12 12:26 PM Re: Anti-TNFs - 75% Increased Risk of Shingles [Re: MollyC1i]
Pea Offline
Gold_AS_Kicker

Registered: 02/24/11
Posts: 1542
Loc: Pacific Northwest
Okay Steve,

Thank's for letting me know that. It seems really odd to me that I have not gotten the flu once since my A.S. came out of remission. I don't know if it is because I am housebound, I wear gloves all the time and don't take them off at the grocery store or any other store and use a lot of hand sanitizer. I ask people before they come over if they are sick.
_________________________
Pea
Diagnosed with A.S. 26 year's ago.
Diagnosed with Fibro 9 year's ago.
Sulphasalazine, Folic Acid, Remicade

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