Rapid response to adalimumab (Humira) was the strongest predictor of sustained remission among patients with ankylosing spondylitis, a long-term extension study found.

On multivariate analysis, patients with this inflammatory arthritis of the spine who achieved partial remission by week 12 of treatment had a hazard ratio of 2.49 (95% CI 1.40 to 4.43, P=0.002) for maintaining that degree of response up to 5 years, according to Joachim Sieper, MD, of University Clinic Benjamin Franklin in Berlin, and colleagues.

And those who reached a state of inactive disease by 3 months had a hazard ratio of 3.18 (95% CI 1.83 to 5.53, P<0.001) for maintaining remission, Sieper and colleagues reported in the May Annals of the Rheumatic Diseases.

The Assessment in Spondyloarthritis International Society recommends that response to anti-tumor necrosis factor treatment be assessed at 3 months to determine if the therapy should be continued.

http://www.medpagetoday.com/Rheumatology/BackPain/32144

This is very encouraging! It's been a week after my first Humira shot and i can not believe the so drastic difference already (started from day #2) I hope my immune system will be rebooted and get fixed as a computer running windows :-P

AHA! This must be the problem. I want my immune system reinstalled with Linux!!!!!!

I had almost immediate results when I started Humira. It's now been about 2 years and it's still working!!! The drugs I have tried in the past (notably Remicade) gave good initial results, but the benefit wore off after a year or two.

Keeping my fingers crossed. (at least as far as they will).