anyone know if CRP levels are elevated with IBS? (NOT IBD)

http://www.ncbi.nlm.nih.gov/pubmed/21951717

the conclusion part at the end of this article,am i reading it right...CRP in someone with IBS is usually raised but within normal levels?

answering my own questions here...:)

link below says IBS does not increase CRP levels

http://www.patient.co.uk/health/Irritable-Bowel-Syndrome.htm

Since IBS is more of functional problem and IBD is inflammatory, yes it stands to reason that CRP would not be elevated. <smile> You are correct.

You are right - that first link says that there can be a mild inflammatory reaction going on with IBS.

I'd really wonder if the people that this happens in possibly do actually have IBD, but not severe enough (or accessible enough to scoping) that it has been positively confirmed on examinations or biopsy. It would seem to me that it would be really easy to get false negatives on biopsies, because if you don't happen to get the scope quite far enough along, or its patchy damage, then you could miss it. The absence of evidence wouldn't necessarily mean the absence of the disease. I know there is a bit of a warning with coeliac disease with that - coeliac damage can be quite patchy and can start quite low down, so that an endoscopy could well miss it even if it is there.

If you are talking about the UK, then I would say quite a few people with IBS diagnosed could really have IBD (or coeliac) - IBS is only meant to be diagnosed after ruling out IBD, but they don't do colonoscopies here anywhere near as often as they do in the US. I know I have had IBD ruled out on the basis of a sigmoidoscopy that actually didn't get much further than the rectum (inadequate prep ordered too late by stoopid young intern) and a single rectal biopsy. I've heard of quite a few other folk who have had GPs diagnose IBS with no investigation or referral.