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#452800 - 09/23/11 11:37 AM Inglammatoy Eye Disease - Curcumin
MollyC1i Offline

Registered: 01/21/04
Posts: 9594
Loc: Brittany, France (since Nov 08...
Curcumin has been implicated in the treatment of certain eye diseases and conditions, including chronic anterior uveitis, an inflammatory condition of the vascular layer, particularly the iris. In a small study, curcumin (375 mg t.i.d.) was administered orally for 12 weeks to 32 patients with chronic anterior uveitis. The participants were divided into two groups; the first received only curcumin while the second was treated with a combination of curcumin and antituber- cular therapy. All patients treated with curcumin alone improved, compared with a response rate of 86% among those receiving the combination therapy (42). Recently, a study was conducted on curcumin’s potential to treat dry eye disease and to protect against hyperosmosis-induced IL-1β elevation via MAPK pathways in human corneal epithelial cells. Human corneal epithelial cells cultured in the hyperosmotic medium for 24 h showed an increase of IL-1β, IL-6 and TNF-α levels. Curcumin (1–30 µM) did not affect the viability of cultured corneal epithelial cells, but pretreatment with curcumin (5 µM) completely abolished the increased production of IL-1β, p38 phosphorylation and NF-κB induced by the hyperosmotic medium (43). These studies suggest that curcumin may be an effective therapeutic for a variety of inflammatory eye conditions.

Shehzad A, Lee YS: Curcumin: multiple molecular targets mediate multiple
pharmaological actions -- a review. Drugs of the Future 2010;35:113-119.

MollyC1i - Riding OutAS

#452883 - 09/24/11 05:07 PM Re: Inglammatoy Eye Disease - Curcumin [Re: MollyC1i]
MollyC1i Offline

Registered: 01/21/04
Posts: 9594
Loc: Brittany, France (since Nov 08...
Help - Can't invent my typoes! Strewth, would ya ever look'at that one... Inflammatory (not what my fingers managed to come up with <DOH>)
MollyC1i - Riding OutAS

#453346 - 09/30/11 05:03 PM Re: Inglammatoy Eye Disease - Curcumin [Re: MollyC1i]
MNAnn Offline

Registered: 03/11/04
Posts: 490
Loc: SC
Cool! I'm gonna buy some tomorrow.
mom to three boys 10, 12, 14
Diagnosed with spondylitis in 2004
pharmacist who now seeks natural therapies including NSD & essential oils

#453496 - 10/02/11 07:08 PM Re: Inglammatoy Eye Disease - Curcumin [Re: MNAnn]
zark Offline

Registered: 04/12/02
Posts: 2424
Loc: NSW, Oz
I used to use rutin for my eye inflammation a few years back (an antioxidant) when i had troubles. Not to be used whilst pregnant though
what I can eat on the diet (click here) -- my blog -- contact me (PM is broken)
"Some men, in truth, live that they may eat, as the irrational creatures, 'whose life is their belly, and nothing else.' But the Instructor enjoins us to eat that we may live." -- Clement of Alexandria (about 200 AD)

#455574 - 11/03/11 07:50 PM Re: Inglammatoy Eye Disease - Curcumin [Re: MollyC1i]
jessxo Offline

Registered: 05/20/08
Posts: 285
Loc: NJ (trying to escape somewhere...
Hi there. Hmmm, never heard of cucumin but I'm all about anything that can help with these pesky dry eyes. Thanks for the info!!
KR, Jess
Dx'd AS (seronegative spondylarthopathy), Fibromyalgia 8/2007
Be happy for this moment... This moment is your life.

#455603 - 11/04/11 09:42 PM Re: Inglammatoy Eye Disease - Curcumin [Re: MollyC1i]
Pea Offline

Registered: 02/24/11
Posts: 1968
Loc: Pacific Northwest
I use Clear Kote. I believe it is the only eye drop's that treat all three layer's of the eye. I have tried everything else for dry eye including heated goggle's. You have to have a prescription for it.

I have some Curcumin. My Naturopath gave it to me for pain. It didn't help the pain but I didn't know it help's dry eye's. I will try it again and see if it help's. How long do you take it before you notice any help? Thank's!

Diagnosed with A.S. 29 year's ago.
Diagnosed with Fibro 10 year's ago.
Remicade, Intrathecal Pain Pump 2013

#455754 - 11/07/11 04:54 PM Re: Inglammatoy Eye Disease - Curcumin [Re: jessxo]
Johnthain Offline

Registered: 09/09/11
Posts: 36
Jess I am pretty sure Curcumin is the spice turmeric!!

#455774 - 11/08/11 02:15 AM Re: Inglammatoy Eye Disease - Curcumin [Re: MollyC1i]
MollyC1i Offline

Registered: 01/21/04
Posts: 9594
Loc: Brittany, France (since Nov 08...
Curcumin and Tumeric are one and the same. IF you can find the fresh root curcumin (tumeric) then better still, as fresh. Asian, West Indian outlets might have - know the 'fresh' is diff to find. It is a great root to use in cooking - mighty different to the dried stuff. Fresh looks very like large ginger root, and use the same: peel off outer thin skin, chope fine and put in cookk pot - or make an infusion like with making a ginger tea.

For dry eyes. Hot water is terrific. Just bath eyes in as hot a water as poss (don't scald yourself!) I like to just stand under hot water shower. But during day IF eyes really bothersome then I soak flannel in hot water and copiously bath eyes (cheap, cheerful, works - tip from my UK Prof ophtho consultant).

Also use single application preservative free eye drops. Lovely. As is N'Acetyl Carnosine, cepting N'Acetyl C is flippin expensive...!!
MollyC1i - Riding OutAS


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