Kickas.org Forums Ankylosing Spondylitis General Discussion #1 AS Web Support Group I'm Starting A New Oral Biologic!!

Hi Lon...I owned a huge, white male when I was a teenager...he was awesome and beautiful! Okay, the shedding...they do shed a lot, they "blow coat" twice a year, in late fall, they blow their summer coat so that their winter coat can come in and then in the late spring, they blow their winter coat so that they can get their summer coat, which is lighter than the winter coat..so it happens twice a year and very little in between....also, it depends on the dog to some degree, believe it or not, good coat retention is a breeding target...and they are definitely hardy enough to stay outside and they're wonderful protectors, I'm sure yall heard all the horror stories on the news after Katrina about armed bandits taking over everything down here...the stories are true...anyway, Mike tried to get home before it hit but he didn't make it...I had absolutely no trouble what so ever, none of those thugs would come near me and the kids with the dogs there, we took them everywhere with us as that saga unfolded and we had no trouble...we came across some thugs trying to drag a handicapped woman out of her car so they could carjack her, I opened my truck door and hollered to them that if they didn't let her go and get away from her I was going to let the dogs go on them....they let her go and ran off....I've looked at a couple of pups for yall and I like the lineage on them, they all come from parents with good, sound temperments and they'll make good dogs. Talk to you soon, hugs to Lin...

Epiphany!!.... ....as I enter week 17, something hit me square in the middle of the forehead this morning....several times since beginning this clinical trial I have felt like I was going into a flair, just yesterday, I woke up feeling like the bullet finally found it's target, I felt like I had the flu, but today I feel fine, I think the medicine is keeping the flairs at bay! I've even mentioned it here but it never progresses, I hope I'm right and it's not a coincidence...that would be awesome!

YEA!!! My dose was raised at my appointment yesterday, so everyone in the study group is now on Apremilast, if you were on placebo, they bumped you to 20 mg., if you were on 10 mg., they bumped you to 20 mg., if you were on 20 mg., you were bumped to 30 mg., and those already on 30 mg. were left on the 30 mg. dose. So now, I can't to see if the higher dose will impact my pain levels, I've been anxiously awaiting this leg of the study! This is the actual purpose of the study, to see if Apremilast is an effective treatment for inflammatory diseases if taken in higher doses....

Good luck with it, Michelle!!

Warm hugs,

Thanks Kat! It's been 3 days since my dose was raised and I'm experiencing quite a bit of nausea nausea. The first day it was pretty bad but it's getting better now, I'm sure by next week, this'll be behind me...on the flip side, I woke up an hour earlier than usual this morning and I actually felt rested! WooHoo! I can't wait to see my lab results next week!

Keep it up, Michelle!!

ACK, maybe, under the circumstances, I should say, "Keep it down???"

I'm so glad this has been working so well for you.

Warm hugs,

so how are you feeling?
is your life getting back to normal?

Thanks so much Kat...you're my favorite cheerleader! I'm telling you though, this nausea is debilitating....UGH! It's over by noon though, I hope it doesn't last too long....

Hi Lon...four words...PLOP, PLOP, FIZZ, FIZZ.... Until noon or so, anyway...other than that, I am feeling like I'm 20 again but ir only lasts for about 8 hours and then I'm done, just worn out. I'm thinking that it's just a matter of building up my endurance levels because I'm on the go the whoole eight hours...a little fine-tuning and this'll be awesome!!!

HI.
I have trouble keeping track and finding my way around this site at times. I am wondering how you are doing with all this activity and how you are feeling!?
Bit of a tough patch for me, but some blessings and good things along the way.
Lin is hanging in there.
Lon
I seem to have hadtoo many crisis to think about a dog right now. How much would it cost to ship a dog?
hmm. I did visit you site. I enjoyed it. LS